题目：Breast cancer in association with thyroid disorders
作者：Orhan Turken1, Yavuz NarIn2, Sezai DemIrbas3, M Emin Onde4, Ozkan Sayan5, E Gokhan KandemIr1, Mustafa YaylacI1 and Ahmet Ozturk5
杂志：Breast Cancer Research Vol 5 No 5：110-113
Abstract
Background: The relationship between breast cancer and thyroid diseases is controversial. Discrepant results have been reported in the literature. The incidences of autoimmune and nonautoimmune thyroid diseases were investigated in patients with breast cancer and age-matched control individuals without breast or thyroid disease.
Methods: Clinical and ultrasound evaluation of thyroid gland, determination of serum thyroid hormone and antibody levels, and fine-needle aspiration of thyroid gland were performed in 150 breast cancer patients and 100 control individuals.
Results: The mean values for anti-thyroid peroxidase antibodies were significantly higher in breast cancer patients than in control individuals (P=0.030). The incidences of autoimmune and nonautoimmune thyroid diseases were higher in breast cancer patients than in control individuals (38% versus 17%, P=0.001; 26% versus 9%, P=0.001, respectively).
Conclusion: Our results indicate an increased prevalence of autoimmune and nonautoimmune thyroid diseases in breast cancer patients.
Keywords: breast, cancer, thyroid
题目：乳腺癌和甲状腺疾病的关系
摘要：
背景：乳腺癌和甲状腺疾病的关系有争议。文献中已经有相反的结论报道。在乳腺癌病人和以年龄做对照的非乳腺或甲状腺疾病个体中调查自身免疫和非自身免疫性甲状腺疾病的发病率。
方法：在150例乳腺癌病人和100例对照个体中进行甲状腺的临床和超声评价，测定血清中甲状腺激素及其抗体水平，并行细针甲状腺穿刺。
结果：抗甲状腺过氧化物酶抗体的平均值在乳腺癌病人中较对照组有意义的增高(p＝0.030)。乳腺癌病人中自身免疫和非自身免疫性甲状腺疾病的发病率较对照组增高(38%对17%，p＝0.001；26%对9%，p＝0.001)
结论：我们的结论显示乳腺癌病人中自身免疫和非自身免疫性甲状腺疾病的发病增高。
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