承担课题
(1) "RUNX2基因在乳腺癌转移及EMT中表达的意义及调控机制研究"天津市应用基础及前沿技术研究计划(11JCZDJC28000),第一承担人,20.0万,6/2011至6/2014,进展顺利
(2) "药物代谢酶基因多态性指导乳腺癌新辅助化疗的研究"天津市科委面上项目(07JCYBJC09100),2006-2009,第一承担人(2010年结题)
(3) "巨噬细胞系统在大鼠DIEP乳房再造模型中意义的研究,"天津医科大学科研基金2006-2009,第一承担人(2010年结题)
(4) "巨噬细胞系统在大鼠DIEP乳房再造模型中意义的研究,"天津市卫生局科研基金2006-2009,第一承担人(2010年结题)
(5) "乳腺癌患者来源抗体库的构建",天津市教委重点基金项目(07JCYBJC09100) 2006-2009,第三承担人(2010年结题)
(6) "SLP-2基因在常见恶性肿瘤中的表达及与预后关系研究",天津医科大学科研基金,2005-2007,第五承担人,已结题并成果登记(2008年)
(7) "不同来源TIMP-1表达对肿瘤细胞生物特性影响的研究",天津市卫生局科研基金,2005-2008,第二承担人,已结题,已结题并成果登记(2008年)
发表文章
(1) Xu-Chen Cao, Wei-Ran Zhang, Wen-Feng Cao, Bo-Wen Liu, Fei Zhang, Hong-Meng Zhao, Ran Meng, Lin Zhang, Rui-Fang Niu, Xi-Shan Hao, Bin Zhang. Aquaporin 3 is required for FGF-2-induced migration of human breast cancers. (PLOS ONE,Accepted)
(2) Xu-Chen Cao, Wei-Ran Zhang, Wen-Feng Cao, Bo-Wen Liu, Fei Zhang, Hong-Meng Zhao, Ran Meng, Lin Zhang, Rui-Fang Niu, Xi-Shan Hao, Bin Zhang. PKCδ regulates AQP3-dependent cell migration of human breast cancers via PI3K/AKT/mTOR signaling. (Breast cancer research and treatment, under review)
(3) Han YW, Yu ZH, Wen SY, Zhang Bin, Cao XC and Wang X. Prognostic value of hemotherapy-induced neutropenia in early-stage breast cancer. Breast Cancer Res Treat. 2012 Jan;131(2):483-90. (SCI收录,IF:4.859)
(4) F. Zhang, X. Zhang, M. Li, P. Chen, B. Zhang, H. Guo, W. Cao, X. Wei, X. Cao, X. Hao and N. Zhang .mTOR complex component Rictor interacts with PKCzeta and regulates cancer cell metastasis. Cancer Res. 2011;70(22):9360-70.
(5) Wang X, Zhao Y, Cao X*. Clinical benefits of mastectomy on treatment of occult breast carcinoma presenting axillary metastases. Breast J. 2010;16:32-7.
(6) Zhang B, Cao W, Zhang F, Zhang L, Niu R, Niu Y, Fu L, Hao X, Cao X*. Protein interacting with C alpha kinase 5 (PICK1) is involved in promoting tumor growth and correlates with poor prognosis of human breast cancer. Cancer Sci. 2010 Mar
(7) Chang XZ, Yu J, Zhang XH, Yin J, Wang T, Cao XC*. Enhanced expression of trophinin promotes invasive and metastatic potential of human gallbladder cancer cells. J Cancer Res ClinOncol. 2009;135:581-90.
(8) Zhang B, Cao X, Liu Y, Cao W, Zhang F, Zhang S, Li H, Ning L, Fu L, Niu Y, Niu R, Sun B, Hao X. Tumor-derived matrix metalloproteinase-13 (MMP-13) correlates with poor prognoses of invasive breast cancer. BMC Cancer. 2008;8:83.
(9) Cao W, Zhang B, Liu Y, Li H, Zhang S, Fu L, Niu Y, Ning L, Cao X, Liu Z, Sun B. High-level SLP-2 expression and HER-2/neu protein expression are associated with decreased breast cancer patient survival. Am J ClinPathol. 2007;128:430-6.
(10) Li X, Cao X, Li X, Zhang W, Feng Y. Expression level of insulin-like growth factor binding protein 5 mRNA is a prognostic factor for breast cancer. CancerSci. 2007 ;98:1592-6.
(11) Niu Y, Fu XL, Yu Y, Wang PP, Cao XC*. Intra-operative frozen section diagnosis of breast lesions: a retrospective analysis of 13,243 Chinese patients. Chin Med J (Engl). 2007;120:630-5.
(12)冯炜红,张斌,曹旭晨*.上皮-间质转化与乳腺癌.国际肿瘤学杂志,2011,38: 121-123
(13)李媛媛,张斌,曹旭晨*.组蛋白脱乙酰基酶抑制剂在肿瘤治疗中的应用.国际肿瘤学杂志. 2011,38:424-426.
(14)刘博文,张斌,曹旭晨*.树突状细胞免疫治疗的新进展.国际肿瘤学杂志. 2011, 38: 20-23.
(15)陈祖锦,张斌综述,曹旭晨*审校.自噬与肿瘤治疗.国际肿瘤学杂志.2011,38:170-172.
(16)刘博文,张斌,张伟然,张月,冯纬红,李媛媛,曹旭晨*. 3-甲基腺苷对芹菜素诱导乳腺癌T47D细胞系自噬和凋亡的影响.中国肿瘤临床. 2011, 38:1318-1321
(17)刘博文,张斌,张月,冯纬红,李媛媛,张伟然,曹旭晨*.芹菜素诱导乳腺癌T47D细胞株自噬的研究.中华实验外科杂志. 2011,28:2000-2000.
(18)韩芸蔚,王欣,张斌,温绍艳,刘伟,曹旭晨*。新辅助化疗诱导的粒细胞减少症对乳腺癌预后的影响.中华普通外科杂志2011;8:651-654.
(19)宋艳群,张斌,曹旭晨*,赵洪猛,等.阳性淋巴结比率对腋窝淋巴结受累乳腺癌患者总生存率的影响.实用肿瘤杂志,2011, 26:33-36.
(20)宋艳群,张斌,曹旭晨,赵洪猛,等. Akt抑制剂MK2206对乳腺癌细胞增殖和凋亡的影响.肿瘤,2011, 31(2):131-135.
(21)张斌,曹文枫,高宇,潘思虎,刘岩雪,宁连胜,郝希山,曹旭晨*.阳性-检查淋巴结比例(PER)在腋淋巴结阳性乳腺癌的预后意义.中华普通外科杂志.2010; 25: 418-419
(22)张斌,冯锐,潘思虎,曹文枫,刘岩雪,乔群,曹旭晨*.大鼠腹壁动脉穿支皮瓣模型的建立.中华实验外科杂志.2010;27:125-127
(23)赵洪猛,张斌,姚慧,李小莉,宋艳群,王鑫,刘晓霞,曹旭晨*. FGFR2基因多态性与乳腺癌易感性的相关研究.中国肿瘤临床. 2010;37:626-629
(24)宋艳群,张斌,赵洪猛,曹旭晨*.乳腺癌结外浸润对不同水平腋窝淋巴结受累患者预后的影响.中国肿瘤临床.2010;37:862-865
(25)任莉,张斌,曹旭晨,陈瑛,葛洁.荧光定量PCR分析FGFR2基因多态性与乳腺癌的相关性研究.中华医学遗传学杂志2010;27:445-448.
(26)张斌,孟然,赵洪猛,曹旭晨*.隐匿性乳腺癌的临床诊治要点.中国肿瘤临床. 2010; 37: 477-480
(27)陈祖锦,张斌,曹旭晨*.Bcl-2蛋白小分子抑制剂的研究进展.国际肿瘤学杂志. 2010; 37: 579-581
(28)刘博文,张斌,陈祖锦,曹旭晨*.芹菜素抗肿瘤机制研究进展.国际肿瘤学杂志. 2010, 37:824-827.
(29)张月,张斌,冯玮红,曹旭晨*等.Aurora激酶抑制剂对乳腺癌细胞增殖和凋亡的影响.中华实验外科杂志.2012,29:74-76.
(30)张月,张斌,冯玮红,曹旭晨*等.PHA739358抑制乳腺癌细胞增殖、诱导凋亡的分子机制.中华医学杂志.2012,92:45-49.
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