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教学大纲

Introduction To Oncology

OBJECTIVES

Knowledge

At the end of the course the student will be able to:

1. Know well the concept of carcinogenesis.

2. Know well the principle of treatment

3. Describe the diagnostic methods of cancer

4. Describe the classification and anatomic staging of cancer

5. Understand the epidemiology characteristics of cancer

6. Understand the etiology characteristics of cancer

7. Understand the prognosis-related factors of cancer

COURSE CONTENT

Theory

1. Concept of carcinogenesis

2. Epidemiology characteristics of cancer

(1) Incidence change

(2) Age and sex

(3) Race and ethnicity

3. Etiology characteristics of cancer

(1) Environmental and industrial chemical carcinogens

(2) Medical drug-Induced carcinogens

(3) Radiation carcinogenesis

(4) Virus and immunologic mechanisms

(5) Lifestyle

4. Diagnostic methods of cancer

(1) Molecular tumor markers

(2) Typical clinical presentations

(3) Early clinical detection

(4) Screening procedures

(5) Molecular pathology of cancer

(6) Oncologic imagingCTMRIB-usPET/CT

5. Classification and anatomic staging of cancer

(1) The objectives of classification

(2) Histopathologic classification

(3) Anatomic staging and classification (TMN classification)

6. Principles of treatment

(1) Surgical treatment principles

(2) Radiation treatment principles

(3) Medical treatment principles

7. Prognosis-related factors of cancer

(1) The concept of mortality rate

(2) The concept of morbidity rate

ETIOLOGY and ETIOLOGY of CANCER

OBJECTIVES

Knowledge

At the end of the course the student will be able to:

1. Cancer incidence and mortality;

2. Difference of cancer incidence and cancer prevalence;

3. Significance of cancer registry;

4. Cancer distribution in gender and geography;

5. Epidemiological information of common cancers;

6. Risk factors caused cancer and prevention ;

7. Etiological factors of several common cancers

 

Skills

At the end of the course the student will be able to:

1. Understand the definition of cancer incidence and mortality;

2. Distinguish the difference of cancer incidence and cancer prevalence;

3. Know worldwide cancer prevalence and distribution in gender and geography;

4. Etiology and prevention of common malignant tumors;

 

COURSE CONTENT

1. Global cancer burden

2. Cancer registry and statistics

3. Gender and geographic variability of cancer

4. Several common cancers’ epidemiological information

5. Cancer risk factors and prevention

6. Cancer etiology by site-specific cancer

 

Pathology of Neoplasm

OBJECTIVES

Knowledge

At the end of the course the student will be able to:

1. Understand the concepts of definition, nomenclature and morphology of neoplasma.

2. Have a knowledge of atypia, differentiation and anaplasia of neoplasma.

3. Understand the growth and spread of neoplasma.

4. Master the rules of grading and staging of tumors.

5. Have knowledge of clinical features of neoplasma.

6. Have an understanding of etiology, epidemiology and diagnosis of tumors.

7. Know the common typies of human tumors.

 

Skills

At the end of the course the student will be able to:

1. Distinguish the benign tumors with the malignant tumors by the nomenclature.

2. Differentiate the common benign and the malignant tumors according to the gross appearance and microscope morphology of tumors.

3. Give the proper histological grading of the malignant tumors.

4. Use the TNM system giving the right staging of the malignant tumors.

5. Master the general methods of pathologic diagnosis for the neoplasmas.

6. Have a knowledge of the tumor markers.

7. Judge the histological type of tumors.

 

COURSE CONTENT

Theory

1. Definitions, nomenclature and morphology

(1) Definitions

① Scientific definition

Three important features in neoplastic hyperplasias, especially malignant tumors.

i. Excessive hyperplasia

ii. Abnormal differentiation

iii. Persistent and progressive

(2) Nomenclature

① Nomenclature of benign tumors.

② Nomenclature of malignant tumors.

Special nomenclature for some neoplasm’s

The different characteristics of both benign and malignant tumors

(3) Morphology

① Gross appearance of tumors

② Histological structure of tumors

i. parenchyma

ii. stroma

2. Atypia, differentiation and anaplasia of neoplasms

(1) Atypia

① Architectural atypia

② Cytologic atypia

i. Nuclear pleomorphism

ii. Cytoplasmic changes

(2) Differentiation

(3) Anaplasia

3. Growth and spread of neoplasma

(1) Growth

① Rates of growth

② Pattern of growth

i. Growth by expansion

ii. Growth by infiltration

iii. Exophytic growth

(2) Spread of neoplasms

①Direct spreading

② Metastasis

i. Lymphatic metastasis

ii. Hematogenous metastasis

iii. Seeding metastasis

③ Process and mechanisms of spread

4. Grading and staging of tumors

(1) Grading of tumors

(2) Staging of tumors (the most widely applicable TNM staging system)

i. T: tumor

ii. N: involvement of local lymph nodes

iii. M: presence of distant metastases

5. Clinical features of neoplasma

(1) Effects of tumor on host

① Local and hormonal effects

② Cancer cachexia

③ Paraneoplastic syndromes

④ Summary of common clinical features

(2) Laboratory diagnosis of cancer

① Morphologic methods

i. Cytologic smears

ii. Biopsy

iii. Immunocytochemistry

iv. Flow cytometry

② Biochemical assays

③ Molecular diagnosis

6. Etiology, epidemiology and diagnosis of tumors

(1) Etiology of tumors

(2) Epidemiology of tumors

(3) Diagnostics of tumors

7. Brief introduction of common tumors

(1) Epithelial tumors and related lesions

① Squamous cell tumors

i. Squamous cell papilloma

ii. Atypical hyperplasia and carcinoma in site

a) Mild atypical hyperplasia

b) Moderate atypical hyperplasia

c) Severe atypical hyperplasia

iii. Carcinoma in situ

iv. Squamous cell carcinoma

② Glandular tumors

i. Adenoma

a) Papillary adenoma

b) Tubular adenoma

c) Papillotubular adenoma

ii. Adenocarcinoma

a) papillary adenocarcinoma

b) Tubular adenocarcinoma

c) Mucinous adenocarcinoma

d) Signet-ring cell carcinoma

(2) Mesenchymal tumor

① Benign mesenchymal tumors

i. Lipoma

ii. Angiolipomas

iii. Leiomyoma

iv. Chondromas

v. Granular cell tumor

vi. Fibroma

vii. Haemangiomas

② Malignant mesenchymal tumors

i. Malignant fibrous histiocytoma (MFH)

ii. Fibrosarcoma

iii. Liposarcoma

iv. Rhabdomyosarcoma

v. Leiomyosarcoma

vi. Synovial sarcoma

vii. Pleural mesothelioma

viii. Malignant vascular tumors

 

 

 

 

 

HEAD AND NECK TUMORS

OBJECTIVES

Knowledge

At the end of the course the student will be able to:

1. Know well the general concept of thyroid cancer and its treatment principles.

2. Have an understanding of squamous cell carcinomas (scc) of the head and neck and the theory of chemotherapy.

3. Understand the concept of the nasopharynx cancer(npc)and its clinical features.

4. Understand the general concept of paranasal sinus cancer

5. Have a knowledge of tumors of the salivary glands.

Skills

In the end of the course the student will be able to:

1. Usual symptom of thyroid cancer and its diagnosis.

2. Four main treatment methods for scc.

3. Radiationtherapy for (npc).

4. Main detection and diagnosis of paranasal sinus cancer

5. Bimaual examination of salivary glands

 

COURSE CONTENT

1. Thyroid cancer

(1) Anatomy of thyroid

Location of the recurrent laryngeal nerve

(2)Histopathology and etiology

Four types of thyroid cancer.

(3)Detection and diagnosis

①The usual symptom of thyroid cancer

② Fine needle aspiration

③ X-ray and ultrasonography

④ CTMRIPET/CT

(4) Treatment

①Theory for total thyroidectomy in western countries.

②Theory for partial thyroidectomy in asia countries.

③Three types of neck dissection

④Complications of surgery

⑤Theory of thyroid hormone therapy after operation.

(5)Prognosis

Main prognosis factors related to thyroid cancer

2. SCCs of the head and neck

(1) Pathology and etiology

(2) Detection and diagnosis

①Usual symptom of SCCs

②Method of bimanual palpation.

(3) Treatment

①Goals of treatment in head and neck oncology

②Four main treatment methods for SCC

③General principles of surgical resection.

④Advantage of radiotherapy

⑤Role of chemotherapy and its theory

(4) Prognosis

3. Tumors of the nasopharynx

(1) Pathology and etiology

①Variety of histopathology

②Pathogenesis

(2) Detection and diagnosis

①Usual presentations of nasopharynx

②Main organ of metastases.

③Nasopharyngoscope

(3) Treatment

①Reason for radiotherapy in npc

②Adjuvant chemotherapy

③Application of surgical resection

(4) Prognosis

4. Paranasal sinus cancer

(1) Pathology and etiology

①Four paranasal sinuses and its location

②Variety of histopathology

(2) Detection and diagnosis

①Typical presentations of paranasal sinus cancer

② CTMRI

③ Rhinoscopy, sinoscopy,

(3) Treatment

①Combined surgicalradiotherapeutic therapy

②Reconstruction

(4) Prognosis

5.Tumors of the salivary glands

(1)Aanatomy

①Three major salivary glands

②Adjuvant structures of parotid gland and submandibular gland

(2) Pathology and etiology

Variety of histopathology

(3)Detection and diagnosis

①Usual symptom of salivary gland tumors

②Malignant features of parotid tumors

③Obstruction of the submandibuler duct or inflammation of the gland

④The method of bimaual examination

⑤X-ray and ultrasonography

(4) Treatment

①Indication of surgery

②Role of radiotherapy in salivary gland tumors

(5)Prognosis

Surgery of Breast Tumor

OBJECTIVES

Knowledge

At the end of the course the student will be able to:

1. Describe the anatomy of breast

2. Choose tests, imaging, and diagnostic studies and procedures helpful in confirming the diagnosis and in guiding surgical decisions

3. Rrecognize associated histolopathologic findings, classifications and staging ;

4. Discuss outcome, prognosis, future surgical improvements, and ongoing controversies.

 

Skills

In the end of the course the student will be able to:

1. Diagnose a mass of breast by medical history, physical examination and auxiliary examination;

2. Interpret the results of imaging exanimation and perform appropriate management;

3. Know principles of operative surgery, including pre-operative, intro-operative and post operative management.

 

COURSE CONTENT

Theory

Anatomy of breast,

Physical exam of benign tumors and cancer.

Laboratory test of benign tumors and cancer

Surgery of breast tumor

CHEST TUMORS

OBJECTIVES

Knowledge

At the end of the course the student will be able to:

1. Know well the general concepts of non small cell lung cancer(NSCLC) and small cell lung cancer(SCLC).

2. Have an understanding of esophageal cancer and the principle of surgical treatment.

3. Have knowledge the concept of the mediastinal tumors.

4. Have knowledge the clinical characteristics of thymoma.

5. Have knowledge of the radiochemotherapy for small cell lung cancer.

 

Skills

In the end of the course the student will be able to:

1. Usual symptom of lung cancer and its diagnosis.

2. Main treatment methods for non small cell lung cancer.

3. Theory of radiochemotherapy for SCLC

4. Diagnosis and main treatment of esophageal cancer.

5. Classifications of mediastinal tumors.

 

COURSE CONTENT

1. Lung cancer

(1) Practical anatomy of lung.

① Structures of pulmonary hilars.

② Brochopulmonary segments.

(2)Histology

Two types of lung cancer.

(3)Diagnosis and staging.

① Clinical manifestations of lung cancer.

② Noninvasive modalities for lung cancer.

③ Invasive modalities for lung cancer.

④ Staging of NSCLC.

(4) Treatment

① Principles and main method of surgical treatment for NSCLC.

② Lymphatic dissection.

③ The complications of surgery.

④ Ajuvant chemoradiotherapy for NSCLC.

⑤ Principles for the treatment of SCLC.

(5)Prognosis

Main prognosis factors related to NSCLC and SCLC.

2. Esophageal cancer(EC)

(1) Histopathology and etiology

(2) Clinical manifestations and diagnosis

①Usual symptom of EC

②Method of diagnosis.

(3) Treatment

① Different surgical choice between western and asian surgeons.

② General principles of surgical resection.

③ Reconstruction of digestive tract.

④Advantage of radiotherapy.

⑤Role of chemotherapy and its theory in the treatment of EC

(4) Prognosis

3. Tumors of mediastinum

(1) Mediastinal anontomy

① Compartment model of mediastinum

② Common tumors at different compartment

(2) Clinical manifestations and diagnosis

① Usual presentations of mediastinal tumors

② Non-incursions methods for diagnosis

③ Surgical approaches to biopsy.

(3) Treatment

① Treatment of thymoma

② Management of myasthenia gravis

(4) Prognosis

 

HEPATOBILIARY TUMORS

OBJECTIVES

Knowledge

At the end of the course the student will be able to:

1. Main steps of the development of hepatobiliary surgery

2. Liver anatomy

3. Benign liver tumors

4. Primary liver cancer (HCC)

(1) Risk factors

(2) Surveillance and prevention

(3) Diagnosis

① Imaging examination

② Laboratory tests

③ Staging systems

(4) Treatment

① Curative treatments

② Palliative treatments

5. Metastasis liver cancer

6. Cholangiocarcinoma

 

Skills

At the end of the course the student will be able to:

1. Liver anatomy

The eight segments division and blood supply of the liver

2. Benign liver tumors

(1) The most common benign tumors of liver

(2) Differential diagnosis of human heamangioma and HCC

3. Primary liver cancer (HCC)

(1) Risk factors

(2) Mass screening

(3) Diagnosis: imageology examinations and laboratory tests

(4) Treatment: urative hepatectomy, liver transplantation, RFA, TACE, PEI, medication

(5) Prognostic factors

4. Metastasis liver cancer: the most common metastasis cancer of liver

5. Cholangiocarcinoma:, classification,diagnosis

 

COURSE CONTENT

Theory

At the end of the course the student will be able to:

1. Main steps of the development of hepatobiliary surgery

2. Liver anatomy

(1) The eight segments division of liver anatomy

(2) Blood supply of the liver: portal vein, arteriae hepatica

3. Benign liver tumors

(1) The most common benign tumors of liver

(2) Hepatic heamangioma

① Clinical symptom and sign

② Imaging examination

③ Treatment principles

(3) Liver cell adenomas

4. Primary liver cancer (HCC)

(5) Risk factors

(6) Epidemiology and prevention

(7) Diagnosis

④ Imaging examination

⑤ Laboratory tests

⑥ Staging

(8) Treatment

① Curative treatments

② Palliative treatments

5. Metastasis liver cancer

(1) The most common metastasis cancer of liver

(2) Metastatic colorectal cancer

(3) Metastatic breast cancer

(4) Metastatic pancreas cancer

(5) Metastatic Melanoma

6. Cholangiocarcinoma

(1) Clinical symptom and sign

(2) Diagnosis

① Radiological studies

② Laboratory tests

(3) Classification

(4) Treatment options

 

GASTRIC CANCER

OBJECTIVES

Knowledge

At the end of the course the student will be able to:

1. Describe epidemiology and etiology of gastric cancer;

2. Describe prevention and early detection in gastric cancer;

3. Define pathology of gastric cancer, both histological and gross type;

4. Enumerate clinical features of gastric cancer;

5. Describe diagnostic principles of gastric cancer;

6. Define staging and assessment of gastric cancer: Dukes’s and TNM System;

7. Describe treatment of gastric cancer;

(1) Primary therapy: radical operation and palliative operation;

(2)Adjuvant therapy: chemotherapy and irradiation;

(3) Biological therapy (immunotherapy);

8. Define the prognostic factors of colorectal cancer.

 

Skills

At the end of the course the student will be able to:

1. Diagnose gastric cancer;

2. Plan various laboratory tests for patients and interpret the results;

3. Provide primary treatmernt for a patient of gastric cancer;

4. Acquire principles of operative surgery, including pre-operative, operative and post operative care and monitoring.

 

COURSE CONTENT

1. Epidemiology and etiology

2. Prevention and early detection

3. Pathology

4. Clinical presentation

5. Diagnosis

6. Staging and assessment

7. Treatment

8. Prognosis

COLORECTAL CANCER

OBJECTIVES

Knowledge

At the end of the course the student will be able to:

1. Describe epidemiology and etiology of colorectal cancer.

2. Describe screening and prevention in colorectal cancer.

3. Define histopathology classification of colorectal cancer.

4. Define the diagnosis and staging of colorectal cancer: enumerate clinical features of colon cancer and rectal cancer;

5. Describe treatment of colorectal cancer

(1) Surgical therapy: colon cancer, rectal cancer, emergency surgery, liver resection;

(2)Adjuvant therapy: chemotherapy, irradiation and biological therapy

8. Enumerate the content of surveillance.

Skills

At the end of the course the student will be able to:

1. Diagnose colorectal cancer;

2. Plan various tests for patients and interpret the results;

3. Provide primary treatment for a patient of colorectal cancer;

4. Acquire principles of operative surgery, including pre-operative, operative and post operative care and monitoring.

 

COURSE CONTENT

1. Epidemiology and etiology

2. Screening and prevention

3. Pathology

4. Diagnosis and staging

5. Treatment

6. Surveillance

 

GYNECOLOGICAL CANCER

OBJECTIVES

At the end of the course the student will be able to:

1. Master basal knowledge about the most common gynecological cancer

(1) Cervical carcinoma

(2) Endometrial carcinoma

(3) Ovarian cancer

2. Master basal skill about gynecological cancer

(1) Ask medical history

(2) Gynecologic examination

(3) Grasp the special diagnostic methods about various gynecological cancer

 

COURSE CONTENT

1. Cervical carcinoma

(1) Brief indroduce

(2) Epidemiology

① Incidence and prevalence

② Risk factors

(3) Symptoms and signs

① Symptoms and signs of cervical cancer

② Three types of primary tumour

(4) Diagnosis

① Pap smear

② Pelvic examination

③ Imaging examinations

④ Other diagnostic tests

(5) Staging

(6) Main patholohistology types

(7) Main treatment methods

① Surgical treatment

② Radiation

③ Chemotherapy

(8) Prognosis

(9) Prevention

2. Endometrial carcinoma

(1) Epidemiology

① Incidence and prevalence

② Risk factors

(2) Symptoms and signs

(3) Diagnosis

(4) Classification

① Staging of cancer

② Grading of cancer

③ Patholohistological types of cancer

(5) Treatment

(6) Prognosis

(7) Follow-up

(8) Treatment of recurrent cancer

3. Ovarian cancer

(1) Brief indroduce

(2) Epidemiology

① Incidence and prevalence

② Risk factors

(3) The major classification of ovarian cancer

① epithelial tumors

② germ cell tumors

③ sex cord-stromal cell tumors

(4) Symptoms and signs

(5) Diagnosis

① Ask medical history

② Pelvic examination

③ Imaging examinations

④ Other diagnostic tests

(6) Staging of cancer

(7) Grading of cancer

(8) Main treatment methods

① Surgical treatment

② Chemotherapy

③ Radiation

④ Other forms of therapy

(9) Follow-up

Oncologic Imaging

OBJECTIVES

Knowledge

At the end of the course the student will be able to:

1. The imaging features of 3 types of primary lung carcinoma (centralperipheral and diffuse type)

2. The imaging features appearances of mediastinal tumors (thymoma and neurogenic neoplasm)

3. The imaging features of HCC

4. The imaging features of breast carcinoma on mammogram and MRI

 

Skills

At the end of the course the student will be able to:

1. Clinical application of X-ray, CT and MRI

2. Imaging features of pulmonary metastastes

3. Imaging features of hepatic hemangioma

4. Features of breast fibroadenoma on mammogram and MRI

 

COURSE CONTENT

General principles

1. History

2. Clinical application of radiography

3. CT Examination methods & clinical applications

4. Advantages and disadvantages of MRI

Chest

1. Technical considerations

2. Normal X-ray anatomy

(1) Chest wall

(2) Mediastinum

(3) Trachea and bronchi

(4) Lung lobes and lung field

3. Normal CT anatomy

4. Pulmonary tumor

(1) Primary bronchogenic carcinoma

① WHO classification

② Imaging classification

A. Central type

B. Peripheral type

C. Diffuse type

③ Spread of lung cancer

④ Other malignant primarily tumors

(1) Pulmonary metastases

(2) Benign tumors- hamartoma

5. Mediastinal tumor

(1) Thymoma

(2) Teratoma

(3) Lymphoma

(4) Neurogenic neoplasm

Liver and Pancrease

1. Normal anatomy of liver

2. Common diseases of the liver

(1) Hepatic cyst

(2) Hepatic abscess

(3) Cavernous haemangioma

(4) Fatty liver

(5) Hepatic cirrhosis

(6) Hepatocellular carcinoma (HCC)

(7) Cholangiocarcinoma

(8) Hepatic metastasis

3. Normal anatomy of pancreas

4. Common diseases of pancreas

(1) Pancreatitis

(2) Neoplasm

① Ductal adenocarcinoma of pancreas

② Islet cell tumors of the pancreas

Breast

1. The X-ray anatomy of normal breast

2. Common diseases of the breast

(1) Mastitis and breast abscess

(2) Fibroadenomas

(3) Breast cancer

 

 

RADIOTHERAPY

OBJECTIVES

Knowledge

1At the end of the course the student will be able to:

1. Introduction of radiotherapy

(1) Brief History of radiotherapy

(2) Basic concepts of radiotherapy

 

2. Clinical radiobiology
(1) Basic concepts of radiobiology

 

(2) Basic principle of the rays action.

(3) Fractionation of evaluating radiochemy

3. Radiation physics

(1) Basic concepts of radiation physics.

 

(2) Equipment of radiation therapy.

(3) Simple course of radiation therapy.

(4) Technique of radiation therapy.

 

Skills

At the end of the course the student will be able to:

1. Clinical Radiobiology

 

(1) Goal of radiotherapy,

(2) The concept of Radiobiology

(3) The target of Radiotherapy: DNA

(4) Direct effect, Indirect effect.

(5) The cause of oxygen effect

(6) Early-responding tissues, late-responding tissues.

(7) Fractionation of radiotherapy: repair of sublethal, reoxygenation, redistribution, repopulation

2. Radiation physics

(1) Concepts of dose.

(2) Brachytherapy and teletherapy equipment.

(3) The dose characteristics of high energy X-rays and electronics rays

(4) The simple course of radiation therapy.

(5) Conformal radiotherapy, intensity modulated radiotherapy(IMRT), Stereotactic radiotherapy.

 

COURSE CONTENT

Theory

1. Principles of radiotherapy

(1) Brief HistoryThe goal of radiotherapy.

(2) Basic Concepts of Radiotherapy.

 

2. Clinical Radiobiology
(1).The concept of Radiobiology

(2). The target of Radiotherapy: DNA

(3). Direct effect, Indirect effect.

(4). The cause of oxygen effect

(5). Early-responding tissues, late-responding tissues.

(6). Fractionation of radiotherapy: repair of sublethal, reoxygenation, redistribution, repopulation

(7). The criteria in research for evaluate the effect of radiotherapy.

3. Radiation physics

(1) Basic Concepts of Radiation physics. Dose.

(2) The equipment and basic technique of Radiation therapy.

(3) The simple course of Radiation therapy.

(4) The advanced technique of Radiation therapyConformal radiotherapy, intensity modulated radiotherapy(IMRT), Stereotactic radiotherapy.

 

Radiation Oncology

OBJECTIVES

Knowledge

Lung cancer

At the end of the course the student will be able to:

1. The principle of multi-disciplinary treatment for lung cancer

2. Curative radiotherapy for non-small cell lung cancer

3. Post-operative radiotherapy for non-small cell lung cancer

4. Chemo-radiotherapy for non-small cell lung cancer

5. Treatment principle for small cell lung cancer

6. Radiotherapy for small cell lung cancer

7. Radiotherapy for superior vena cava syndrome

8. Progress of radiation oncology for lung cancer (fraction, conformal therapy, IMRT)

Esophageal carcinoma

1. The principle of radiotherapy for esophageal carcinoma

2. Radical radiotherapy for esophageal carcinoma

3. Post-operative radiotherapy for esophageal carcinoma

4. New adjuvant radiotherapy for esophageal carcinoma

5. Concomitant chemo-radiotherapy for esophageal carcinoma

Breast cancer

1. The principal of multi-disciplinary treatment for early stage breast cancer

2. Tangential field radiotherapy after breast conservation operation

3. The progress of radiotherapy for early stage breast cancer

4. The principal of radiotherapy for patient receive radical resection

5. Post-operative radiotherapy for patient receive radical resection

6. Radiotherapy for recurrence disease

Cervical carcinoma

1. clinical staging and treatment principle

2. Pelvic teletherapy

3. Brachytherapy for cervical carcinoma

Radiotherapy for metastasis disease

1. brain metastasis

2. bone metastasis

3. lung metastasis

Skills

At the end of the course the student will be able to:

1. Mastering the diagnosis and differential diagnosis

2. Mastering the indications and contra-indications of radiotherapy for each cancer

3. Technology of radiotherapy

4. Dose and field

5. Complications and treatment

COURSE CONTENT

Theory

1. Relative basic knowledge

2. Staging and treatment principle of radiotherapy

3. Technology of radiotherapy

4. Complications and management

5. Progress of radiation oncology

PRACTICALS

1. Image diagnosis

2. Physical examination

3. Simulation

4. Contour for target volume and treatment planning system

5. Linear accelerator

TEACHING – LEARNING METHODOLOGY

The general pattern of teaching methodology followed by all the faculty members and teaching staff in the department is:

1. Didactic lectures

2. Video showing

3. Discussion

4. Clinical practice

CHEMOTHERAPY

OBJECTIVES

Knowledge

At the end of the course the student will be able to:

1. Understand principles of chemotherapy

(1) Brief history

(2) Characteristics of cancer

(3) Basic concepts of chemotherapy

 

(4) Tumor response to chemotherapy

2. Know well clinical trials
(1) Importance of clinical trials to the practice of medicine

 

(2) How clinical trials differ from other designs of observational study

(3) The advantages and limitations of the design

 

Skills

In the end of the course the student will be able to:

1. Principles of chemotherapy

 

(1) Purpose of chemotherapy

(2) Classification of response

 

(3) Types of chemotherapy

2. Clinical trials
(1) Different types of clinical trials

 

(2) Phases of clinical trial

(3) Design of clinical trials

 

COURSE CONTENT

Theory

1. Goals of chemotherapy

(1) For cure of cancer

(2) For control of cancer

(3) For palliation of symptoms of cancer

2. Type of chemotherapy

(1) Cure/ Control:

① Single chemotherapy

② Adjuvant chemotherapy

③ Neo- adjuvant chemotherapy

④ Concurrent chemotherapy

(2) Palliative chemotherapy

 

3. Classification of response

(1) Complete response

(2) Partial response

(3) Stable disease

(4) Disease progression

4. Trials for FDA Approval of New Therapies

(1)Phase I Safety of therapy is tested in a few normal volunteers (uncontrolled, unblinded)

(2) Phase II Small controlled trial to test tolerability and dose effects on short term outcomes in affected individuals

(3) Phase III Large controlled trial to test the effect of the therapy on clinical outcomes

(4) Phase IV Post-approval surveillance studies to discover serious side effects in large simple & evaluate additional therapeutic uses

PRACTICALS

1. Randomized clinical trial design

2. Evaluation for tumor response

INTEGRATIVE ONCOLOGY

 

OBJECTIVES

Knowledge

At the end of the course the student will be able to:

1. Understand general concept of integrative oncology

2. Understand why we need integrative oncology

3. Understand the basic principles of integrative oncology

4. Comprehend the difference and relationship between traditional therapy (surgery, chemotherapy, radiotherapy and biotherapy) and integrative therapy.

 

Skills

At the end of the course the student will be able to:

1. Understand when patients need integrative therapy

2. Comprehend how to integrate alternative medicine into western medicine in oncology

 

COURSE CONTENT

Theory

1. What is integrative oncology?

2. The history and the future of integrative oncology

3. Why patients need integrative oncology?

4. When then patients need integrative therapy?

5. How could we execute integrative therapy?

6. The main mechanism of action of integrative therapy

PRACTICALS

1. Diet/Nutrition/Nutritional supplements

2. Mind-body therapies (including Qigong and Psychotherapy)

BIOLOGIC THERAPY OF CANCER

OBJECTIVES

Knowledge

At the end of the course the student will be able to:

1. Know well the general principles of biologic therapy.

2. Have an understanding of new approaches of biologic therapy.

3. Understand the concept of clinical application of biologic therapy.

4. Understand the new advances in biologic therapy of cancer.

Skills

At the end of the course the student will be able to:

1. Understand the practice of cytokine therapy.

2. Understand the practice of cell therapy.

3. Understand the practice of antibody therapy.

4. Understand the practice of cancer vaccines.

5. Understand the practice of gene therapy.

 

COURSE CONTENT

Theory

1. Cytokine therapy

(1) Interleukins

(2) Interferon

(3) Colony-Stimulating factors

(4) Tumor necrosis factor

2. Cell transfer therapy

(1) Basic principles

(2) Clinical applications

(3) Melanoma

(4) Renal cell carcinoma

3. Monoclonal antibody therapy

(1) Basic principles

(2) Clinical applications

(3) B-cell lymphomas

(4) Breast cancer

4. Cancer vaccines

(1) Cancer antigens

(2) Basic principles

(3) Clinical applications

(4) DC vaccines

5. Gene therapy

(1) Basic principles

(2) Clinical applications

(3) Suicide gene therapy

 

PRACTICALS

1. Collect peripheral blood stem cell by using CS3000 system.

2. Do the cell culture and tissue culture

3. Observing the infusion of the cells.

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